
On June 30, 2015, the FDA did away with the risk classifications A, B, C, D, and X for drugs in pregnancy. Being pregnant is itself a life condition that is inherently risky. The thing is, there is no way to be risk-averse while pregnant.

They have to be made largely on priorities. This means that these decisions cannot be made based just on facts. You cannot Google your way to the right answer. There isn’t a wealth of information on the subject because almost no one wants to test drugs on pregnant or nursing parents. Since many antidepressants, in limited testing, show a low risk to fetuses, doctors often let pregnant people choose what they want to do. I was terrified of losing the tentative sanity I’d spent so long establishing in order to create another person, one who, more than anything, needed a caretaker who was stable enough to love and nourish them. Not even if there was a slightly elevated risk to the health of my developing fetus. So when I found out I was pregnant six years later, I knew that I would not go off the medication. It was like somebody turned down the static in my brain. I did all sorts of talk therapy and took a variety of medications to remedy these afflictions-some worked, some didn’t. My panic knew no toy ownership, only that we were going to all be drowning any moment and all toys should be saved.įrom that first anxiety attack on, I struggled with more anxiety, depression, and obsessive compulsive disorder. When I finally got home, my tiny, five-year-old body bolted through the house, ripped open the sliding glass doors and dragged everything from the backyard inside-my toys, even my brother’s toys. I overheard someone say that if a hurricane hit, we’d all be under water. 2002 10:633-641.The tropical storm whipped the palm fronds outside into a frenzy, while inside my elementary school, I was getting whipped into a frenzy, as well. Bupropion SR Enhances Weight Loss: A 48-Week Double-Blind, Placebo-Controlled Trial.

Wellbutrin XL has an additional approval for seasonal affective disorder (SAD), which is depression that occurs with the changing of seasons, usually in the fall and winter. SR stands for sustained release, and it may be taken twice a day.īoth XL and SR formulations are approved to treat major depressive disorder. XL is an extended-release medication and only needs to be taken once a day. The difference between Wellbutrin XL and Wellbutrin SR lies in the dosing schedule. Some studies suggest that lower levels of dopamine may be linked to obesity. Upropion increases the level of the brain chemical dopamine. The reason bupropion causes some people to lose weight is not known, but it may have to do with its mechanism of action to treat depression. A study of sustained-release (SR) bupropion for smoking cessation found that people using this medication were less likely to gain weight after they stopped smoking. In the same studies, a small percentage of people gained more than 5 pounds: 3% taking 300 mg and 2% taking 400 mg.īupropion may also be used to help people stop smoking.

At a dose of 400 mg, 19% of people lost more than 5 pounds. Studies of Wellbutrin SR show that 14% of people taking a dose of 300 mg per day lost more than 5 pounds. In the same studies, 11% of people gained more than 5 pounds. Studies of Wellbutrin XL show that 23% of people taking a dose of 150 to 300 mg per day lost 5 pounds or more. Weight changes are considered a side effect for both Wellbutrin XL and Wellbutrin SR. Not everyone taking these drugs will experience a change in weight. Both Wellbutrin XL and Wellbutrin SR may cause weight gain or weight loss, but weight loss is more common. Wellbutrin XL and Wellbutrin SR are different formulations of the antidepressant bupropion.
